Exercise-induced airways constriction

Exercise-induced airway constriction.

J. E. COTES Breathlessness is one of a number of symptoms which may limit exercise; it usually does so when the ventilation during exercise approaches a maximal value which is determined by interaction between the drive to respiration and the mechanical properties of the lung. Assessment is based in the first instance on the clinical interview and simple measurements of lung function. Depending...

Mode of action of halothane on histamine-induced airway constriction in dogs with reactive airways.

To determine if clinical concentrations of halothane have direct relaxant effects on airway smooth muscle, the authors compared dose-response curves to histamine in the control state (thiopental) and during halothane anesthesia (1.0 and 1.5 MAC), in six basenji-greyhound (BG) dogs untreated and pretreated with atropine aerosols (10 mg X ml-1). Pulmonary resistance (RL) and dynamic compliance (C...

Effect of airways constriction on exhaled nitric oxide.

While airway constriction has been shown to affect exhaled nitric oxide (NO), the mechanisms and location of constricted airways most likely to affect exhaled NO remain obscure. We studied the effects of histamine-induced airway constriction and ventilation heterogeneity on exhaled NO at 50 ml/s (Fe(NO,50)) and combined this with model simulations of Fe(NO,50) changes due to constriction of air...

Effects of Exercise on the Airways

Maria R. Bonsignore1,4, Nicola Scichilone1, Laura Chimenti1, Roberta Santagata1, Daniele Zangla2 and Giuseppe Morici3,4 1Biomedical Department of Internal and Specialistic Medicine (DiBiMIS), Section of Pneumology, 2Department of Motor Sciences (DISMOT), 3Department of Experiental Biomedicine and Clinical Neurosciences (BIONEC), University of Palermo, 4Institute of Biomedicine and Molecular Imm...

Gastroesophageal reflux-induced bronchial constriction.